TIGIT
An immunoglobin protein from the PVR (poliovirus receptor) family is encoded by this gene. Several kinds of T cells, including follicular B helper T cells, express the gene's product (TFH). It has been demonstrated that the protein has a strong affinity for the PVR molecule; this affinity is considered to support interactions between TFH and dendritic cells that control T cell dependent B cell responses.
Full Name | T cell immunoreceptor with Ig and ITIM domains |
Gene ID | Human: 201633 Mouse: 100043314 Rat: 363784 Monkey: 710941 |
UniProt ID | Human: Q495A1 Mouse: P86176 Rat: D3ZTQ2 Monkey: A0A5F8AKQ5 |
Alternative Names | TIGIT; VSIG9; VSTM3; WUCAM; T-cell immunoreceptor with Ig and ITIM domains; V-set and immunoglobulin domain containing 9; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; VSIG9, VSTM3; Washington University cell adhesion molecule; T cell immunoreceptor with Ig and ITIM domains |
Product List
- Product Category:
- Membrane Protein Tools
- Target Protein: TIGIT Target Family: Immune Checkpoint Vector: pBE Vector Type: Bacterial Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: TIGIT Target Family: Immune Checkpoint RNA Type: IVT mRNA Formation: In Vitro Transcription (IVT) mRNA
- Product Category:
- Membrane Protein Tools
- Target Protein: TIGIT Target Family: Immune Checkpoint Vector: pIVT Vector Type: In Vitro Transcription (IVT) Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: TIGIT Target Family: Immune Checkpoint Vector: pIE Vector Type: Insect Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: TIGIT Target Family: Immune Checkpoint Vector: pLV Vector Type: Lentiviral Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: TIGIT Target Family: Immune Checkpoint
- Product Category:
- Membrane Protein Tools
- Target Protein: TIGIT Target Family: Immune Checkpoint RNA Type: LNP-mRNA Formation: LNP Encapsulation mRNA
- Product Category:
- Membrane Protein Tools
- Target Protein: TIGIT Target Family: Immune Checkpoint Vector: pME Vector Type: Mammalian Transient Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: TIGIT Target Family: Immune Checkpoint Vector: pRV Vector Type: Retroviral Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: TIGIT Target Family: Immune Checkpoint Vector: pYE Vector Type: Yeast Expression Vector
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;Human primary macrophages