TIGIT
An immunoglobin protein from the PVR (poliovirus receptor) family is encoded by this gene. Several kinds of T cells, including follicular B helper T cells, express the gene's product (TFH). It has been demonstrated that the protein has a strong affinity for the PVR molecule; this affinity is considered to support interactions between TFH and dendritic cells that control T cell dependent B cell responses.
| Full Name | T cell immunoreceptor with Ig and ITIM domains |
| Gene ID | Human: 201633 Mouse: 100043314 Rat: 363784 Monkey: 710941 |
| UniProt ID | Human: Q495A1 Mouse: P86176 Rat: D3ZTQ2 Monkey: A0A5F8AKQ5 |
| Alternative Names | TIGIT; VSIG9; VSTM3; WUCAM; T-cell immunoreceptor with Ig and ITIM domains; V-set and immunoglobulin domain containing 9; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; VSIG9, VSTM3; Washington University cell adhesion molecule; T cell immunoreceptor with Ig and ITIM domains |
Product List
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Magic™ Cyno TIGIT HEK293T Cell Line
[CAT#: S01YF-0123-KX125]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TIGIT Target Family: Immune Checkpoint Target Protein Species: Cyno Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Human TIGIT CHO-K1 Cell Line
[CAT#: S01YF-0123-KX120]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TIGIT Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
Magic™ Human TIGIT CHO-K1 Cell Line, Binding assay
[CAT#: S01YF-1022-KX170]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TIGIT Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
Magic™ Human TIGIT HEK293T Cell Line
[CAT#: S01YF-0123-KX321]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TIGIT Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Mouse TIGIT CHO-K1 Cell Line, Binding assay
[CAT#: S01YF-1022-KX171]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TIGIT Target Family: Immune Checkpoint Target Protein Species: Mouse Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
mProX™ Human TIGIT Stable Cell Line
[CAT#: S01YF-1023-PY186]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;Human primary macrophages Assay Types: Biological assays
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