SCN5A
This gene encodes a voltage-gated sodium channel subunit that is tetrodotoxin-resistant and an essential membrane protein. The action potential's initial upstroke in an ECG is caused by a protein that is mostly present in heart muscle. The autosomal dominant heart conditions Brugada syndrome, atrial fibrillation, cardiomyopathy, and long QT syndrome type 3 (LQT3) have all been linked to defects in this gene.
| Full Name | Sodium voltage-gated channel alpha subunit 5 |
| Gene ID | Human: 6331 Mouse: 20271 Rat: 25665 Monkey: 695085 |
| UniProt ID | Human: Q14524 Mouse: Q9JJV9 Rat: P15389 Monkey: F7CEN9 |
| Alternative Names | HB1; HB2; HH1; IVF; VF1; HBBD; ICCD; LQT3; SSS1; CDCD2; CMD1E; CMPD2; PFHB1; Nav1.5; sodium channel protein type 5 subunit alpha; cardiac tetrodotoxin-insensitive voltage-dependent sodium channel alpha subunit; sodium channel protein cardiac muscle subunit alpha; sodium channel, voltage-gated, type V, alpha subunit; voltage-gated sodium channel subunit alpha Nav1.5; SCN5A; Sodium voltage-gated channel alpha subunit 5 |
Product List
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Magic™ mPro Human SCN5A Cell Line
[CAT#: S01YF-1122-KX114]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: SCN5A Target Family: Voltage Gated Sodium Channel Target Protein Species: Human
mProX™ Human SCN5A Stable Cell Line
[CAT#: S01YF-1123-KX5]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: SCN5A Target Family: Voltage Gated Sodium Channel Target Protein Species: Human Host Cell Type: MCF-7; CHO-K1; HEK293
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