PRKD3
This gene belongs to the multigene protein kinase D family of serine/threonine kinases, which bind diacylglycerol and phorbol esters. Members of this family are characterized by an N-terminal regulatory domain comprised of a tandem repeat of cysteine-rich zinc-finger motifs and a pleckstrin domain. The C-terminal region contains the catalytic domain and is distantly related to calcium-regulated kinases. Catalytic activity of this enzyme promotes its nuclear localization. This protein has been implicated in a variety of functions including negative regulation of human airway epithelial barrier formation, growth regulation of breast and prostate cancer cells, and vesicle trafficking.
| Full Name | protein kinase D3 |
| Gene ID | Human: 23683 Mouse: 75292 Rat: 313834 Monkey: 709647 |
| UniProt ID | Human: O94806 Mouse: Q8K1Y2 Rat: D4A229 Monkey: G7PM15 |
| Alternative Names | EPK2; PKD3; PRKCN; PKC-NU; nPKC-NU;serine/threonine-protein kinase D3;protein kinase C nu type;protein kinase EPK2 |
Product List
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mProX™ Human PRKD3 Stable Cell Line
[CAT#: S01YF-1023-PY72]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;A2058 Assay Types: Biological assays
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