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PLK1

The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy.

Full Name polo like kinase 1
Gene ID Human: 5347 Mouse: 18817 Rat: 25515 Monkey: 697686
UniProt ID Human: P53350 Mouse: Q07832 Rat: Q62673
Alternative Names PLK; STPK13;serine/threonine-protein kinase PLK1;PLK-1;cell cycle regulated protein kinase;polo (Drosophia)-like kinase;serine/threonine-protein kinase 13

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Product Category:
Membrane Protein Stable Cell Lines
Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;MG-63
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