PLK1
The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy.
| Full Name | polo like kinase 1 |
| Gene ID | Human: 5347 Mouse: 18817 Rat: 25515 Monkey: 697686 |
| UniProt ID | Human: P53350 Mouse: Q07832 Rat: Q62673 |
| Alternative Names | PLK; STPK13;serine/threonine-protein kinase PLK1;PLK-1;cell cycle regulated protein kinase;polo (Drosophia)-like kinase;serine/threonine-protein kinase 13 |
Product List
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Magic™ Human PLK1 Assay
[CAT#: S01YF-1222-KX457]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: PLK1 Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
mProX™ Human PLK1 Stable Cell Line
[CAT#: S01YF-1023-PY77]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;MG-63 Assay Types: Biological assays
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