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PIK3CD

Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.

Full Name phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
Gene ID Human: 5293 Mouse: 18707 Rat: 366508 Monkey: 710552
UniProt ID Human: O00329 Mouse: O35904 Rat: A0A8I5Y949
Alternative Names APDS; PI3K; IMD14; p110D; IMD14A; IMD14B; ROCHIS; P110DELTA;phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform;PI3-kinase p110 subunit delta;PI3Kdelta;phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta;phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta short variant 8/20;phosphoinositide-3-kinase C;phosphoinositide-3-kinase, catalytic, delta polypeptide variant p37delta;ptdIns-3-kinase subunit p110-delta

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Product Category:
Membrane Protein Stable Cell Lines
Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;OCI-Ly8
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