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PIK3CA

Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22.

Full Name phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
Gene ID Human: 5290 Mouse: 18706 Rat: 170911 Monkey: 709959
UniProt ID Human: P42336 Mouse: P42337 Rat: A0A0G2K344 Monkey: G7NZ32
Alternative Names MCM; CCM4; CWS5; MCAP; PI3K; CLAPO; CLOVE; MCMTC; PI3K-alpha; p110-alpha;phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform;PI3-kinase p110 subunit alpha;mutant phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha;phosphatidylinositol 3-kinase, catalytic, 110-KD, alpha;phosphatidylinositol 3-kinase, catalytic, alpha polypeptide;phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha;phosphoinositide 3-kinase alpha;phosphoinositide-3-kinase, catalytic, alpha polypeptide;ptdIns-3-kinase subunit p110-alpha;serine/threonine protein kinase PIK3CA

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Product Category:
Membrane Protein Stable Cell Lines
Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;MCF-7
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