PDK1
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.
| Full Name | pyruvate dehydrogenase kinase 1 |
| Gene ID | Human: 5163 Mouse: 228026 Rat: 116551 Monkey: 697772 |
| UniProt ID | Human: Q15118 Mouse: Q8BFP9 Rat: Q63065 |
| Alternative Names | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial; pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial;PDH kinase 1;mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1;pyruvate dehydrogenase kinase, isoenzyme 1 |
Product List
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Magic™ Human PDHK1(PDK1) Assay
[CAT#: S01YF-1222-KX426]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: PDHK1(PDK1) Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
mProX™ Human PDK1 Stable Cell Line
[CAT#: S01YF-1023-PY48]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;HCT116 Assay Types: Biological assays
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