NTSR2
This gene encodes a protein that is a member of the family of G protein-coupled receptors that triggers the phosphatidylinositol-calcium second messenger pathway. Studies on binding and pharmacology show that this receptor binds neurotensin as well as a number of additional ligands that have already been mentioned for the neurotensin NT1 receptor. Levocabastine, a histamine H1 receptor antagonist that has previously been demonstrated to compete with neurotensin for low-affinity binding sites in the brain, is recognized by this gene with high affinity in contrast to the NT1 receptor. These actions imply that the receptor may be physiologically significant and that the receptor may have a natural agonist.
| Full Name | Neurotensin receptor 2 |
| Gene ID | Human: 23620 Mouse: 18217 Rat: 64636 Monkey: 697563 |
| UniProt ID | Human: O95665 Mouse: P70310 Rat: Q63384 Monkey: A0A2K5F200 |
| Alternative Names | NTR2; neurotensin receptor type 2; NT-R-2; levocabastine-sensitive neurotensin receptor; neurotensin receptor, type 2; NTSR2; Neurotensin receptor 2 |
Product List
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Magic™ Human FLAG tagged NTSR2 CHO-K1 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX486]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NTSR2 Target Family: Neurotensin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human FLAG tagged NTSR2 HEK293T Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX487]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NTSR2 Target Family: Neurotensin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Magic™ Human NTSR2 (NM_012344.3) CHO-K1 Membrane Preparation
[CAT#: S01YF-0722-KX784]
- Product Category:
- Membranes
- Target Protein: NTS2 Target Family: Neurotensin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human NTSR2 (NM_012344.3) HEK293T Membrane Preparation
[CAT#: S01YF-0722-KX785]
- Product Category:
- Membranes
- Target Protein: NTS2 Target Family: Neurotensin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Application: GTPγS Assay; Ligand Binding Assay
mProX™ Human NTSR2 Stable Cell Line
[CAT#: S01YF-0923-PY144]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NTSR2 Target Family: Neurotensin Family Target Protein Species: Human Host Cell Type: LNCaP;CHO-K1;HEK293 Assay Types: Biological assays
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