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NTSR2

This gene encodes a protein that is a member of the family of G protein-coupled receptors that triggers the phosphatidylinositol-calcium second messenger pathway. Studies on binding and pharmacology show that this receptor binds neurotensin as well as a number of additional ligands that have already been mentioned for the neurotensin NT1 receptor. Levocabastine, a histamine H1 receptor antagonist that has previously been demonstrated to compete with neurotensin for low-affinity binding sites in the brain, is recognized by this gene with high affinity in contrast to the NT1 receptor. These actions imply that the receptor may be physiologically significant and that the receptor may have a natural agonist.

Full Name Neurotensin receptor 2
Gene ID Human: 23620
Mouse: 18217
Rat: 64636
Monkey: 697563
UniProt ID Human: O95665
Mouse: P70310
Rat: Q63384
Monkey: A0A2K5F200
Alternative Names NTR2; neurotensin receptor type 2; NT-R-2; levocabastine-sensitive neurotensin receptor; neurotensin receptor, type 2; NTSR2; Neurotensin receptor 2

Product List

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: NTSR2 Target Family: Neurotensin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: NTSR2 Target Family: Neurotensin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: NTSR2 Target Family: Neurotensin Family Target Protein Species: Human Host Cell Type: LNCaP;CHO-K1;HEK293
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