NTRK3
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.
| Full Name | neurotrophic receptor tyrosine kinase 3 |
| Gene ID | Human: 4916 Mouse: 18213 Rat: 29613 Monkey: 697615 |
| UniProt ID | Human: Q16288 Mouse: Q6VNS1 Rat: Q03351 Monkey: Q5IFJ9 |
| Alternative Names | TRKC; GP145-TrkC; gp145(trkC);NT-3 growth factor receptor;ETS related protein-neurotrophic receptor tyrosine kinase fusion protein;ETV6-NTRK3 fusion;neurotrophic tyrosine kinase, receptor, type 3;tyrosine kinase receptor C |
Product List
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mProX™ Human NTRK3 Stable Cell Line
[CAT#: S01YF-1023-PY119]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;JN-DSRCT-1;SK-DSRCT-2;CHP100
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