NRAS
This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
Full Name | NRAS proto-oncogene, GTPase |
Gene ID | Human: 4893 Mouse: 18176 Rat: 24605 Monkey: 709089 |
UniProt ID | Human: P01111 Mouse: P08556 Rat: Q04970 Monkey: A0A1D5QQS3 |
Alternative Names | NS6; CMNS; KRAS; NCMS; ALPS4; N-ras; NRAS1; GTPase NRas; N-ras protein part 4; neuroblastoma RAS viral (v-ras) oncogene homolog; neuroblastoma RAS viral oncogene homolog; proto-oncogene GTPase; transforming protein N-Ras; v-ras neuroblastoma RAS viral oncogene homolog |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NRAS (G12A) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NRAS (G12C) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NRAS (G12D) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NRAS (G12R) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NRAS (G12S) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NRAS (G13C) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NRAS (G13D) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NRAS (G13V) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NRAS (Q61K) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NRAS (Q61L) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NRAS (Q61R) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;Hep3B;PLC