NR1I2
This gene encodes a triiodothyronine nuclear hormone receptor protein. It has been demonstrated that this thyroid hormone receptor, one of many, mediates the physiologic actions of thyroid hormone. Despite some degree of redundancy, knockout studies in mice reveal that the various receptors may mediate various functions of thyroid hormone. Generalized thyroid hormone resistance (GTHR), a disease characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone, is known to be caused by mutations in this gene.
| Full Name | Nuclear receptor subfamily 1 group I member 2 |
| Gene ID | Human: 8856 Mouse: 18171 Rat: 84385 Monkey: 574226 |
| UniProt ID | Human: O75469 Mouse: O54915 Rat: Q9R1A7 Monkey: Q8SQ01 |
| Alternative Names | BXR; PAR; PRR; PXR; SAR; SXR; ONR1; PAR1; PAR2; PARq; nuclear receptor subfamily 1 group I member 2; orphan nuclear receptor PAR1; orphan nuclear receptor PXR; pregnane X receptor; steroid and xenobiotic receptor |
Product List
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mProX™ Human NR1I2 Stable Cell Line
[CAT#: S01YF-1123-KX113]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NR1I2 Target Family: Vitamin D Receptor Target Protein Species: Human Host Cell Type: PC-3; CHO-K1; HEK293
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