NR1I2
This gene encodes a triiodothyronine nuclear hormone receptor protein. It has been demonstrated that this thyroid hormone receptor, one of many, mediates the physiologic actions of thyroid hormone. Despite some degree of redundancy, knockout studies in mice reveal that the various receptors may mediate various functions of thyroid hormone. Generalized thyroid hormone resistance (GTHR), a disease characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone, is known to be caused by mutations in this gene.
| Full Name | Nuclear receptor subfamily 1 group I member 2 |
| Gene ID | Human: 8856 Mouse: 18171 Rat: 84385 Monkey: 574226 |
| UniProt ID | Human: O75469 Mouse: O54915 Rat: Q9R1A7 Monkey: Q8SQ01 |
| Alternative Names | BXR; PAR; PRR; PXR; SAR; SXR; ONR1; PAR1; PAR2; PARq; nuclear receptor subfamily 1 group I member 2; orphan nuclear receptor PAR1; orphan nuclear receptor PXR; pregnane X receptor; steroid and xenobiotic receptor |
Product List
Loading...
Magic™ Human PXR Agonist & Antagonist Protein-Protein Interaction Assay
[CAT#: S01YF-0822-KX993]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: PXR Target Family: Vitamin D Receptor Target Protein Species: Human Assay Types: Protein-Protein Interaction Assay
Magic™ Human PXR Agonist Radioligand Binding Assay
[CAT#: S01YF-0822-KX994]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: PXR Target Family: Vitamin D Receptor Target Protein Species: Human Assay Types: Radioligand Binding Assay
Magic™ Human PXR Agonist Reporter Assay
[CAT#: S01YF-0822-KX995]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: PXR Target Family: Vitamin D Receptor Target Protein Species: Human Assay Types: Reporter Assay
mProX™ Human NR1I2 Stable Cell Line
[CAT#: S01YF-1123-KX113]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NR1I2 Target Family: Vitamin D Receptor Target Protein Species: Human Host Cell Type: PC-3; CHO-K1; HEK293
Can't find the products you're looking for? Optimize our parameters for better results.
Filter By Tag
Note: All of our products are for Research Use Only (RUO). NOT intended for diagnostic, therapeutic or clinical use. We DO NOT offer patients any direct products or services. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
