MTNR1A
One of two high affinity receptors for melatonin, the main hormone released by the pineal gland, is encoded by this gene. This G-protein coupled, 7-transmembrane receptor is in charge of the melatonin effects on mammalian circadian rhythm and day length-dependent reproductive changes. The receptor is an easily identifiable integral membrane protein that is localized to two distinct parts of the brain. While the hypophysial pars tuberalis may be in charge of the melatonin's reproductive effects, the hypothalamic suprachiasmatic nucleus appears to be engaged in circadian rhythm.
| Full Name | Melatonin receptor 1A |
| Gene ID | Human: 4543 Mouse: 17773 Rat: 114211 Monkey: 702686 |
| UniProt ID | Human: P48039 Mouse: Q61184 Rat: P49218 Monkey: C9WTA9 |
| Alternative Names | MT1; MEL-1A-R; melatonin receptor type 1A; mel1a receptor; MTNR1A; Melatonin receptor 1A |
Product List
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Magic™ Human FLAG tagged MTNR1A CHO-K1 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX432]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MTNR1A Target Family: Melatonin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human MTNR1A CHO-K1 Cell Line, Binding and Functional Assay
[CAT#: S01YF-1222-KX205]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MTNR1A Target Family: Melatonin Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
Magic™ Human MTNR1A CHO-K1/Gα15 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX77]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MTNR1A Target Family: Melatonin receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
Magic™ Human MTNR1A U2OS Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay
[CAT#: S01YF-1222-KX85]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MTNR1A Target Family: Melatonin Receptors Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
mProX™ Human MTNR1A Stable Cell Line
[CAT#: S01YF-0923-PY121]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MTNR1A Target Family: Melatonin Family Target Protein Species: Bovine Host Cell Type: Bovine Granulosa cells;CHO-K1;HEK293
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