MAP2K1
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
| Full Name | mitogen-activated protein kinase kinase 1 |
| Gene ID | Human: 5604 Mouse: 26395 Rat: 170851 Monkey: 710415 |
| UniProt ID | Human: Q02750 Mouse: P31938 Rat: Q01986 |
| Alternative Names | MEL; CFC3; MEK1; MKK1; MAPKK1; PRKMK1;dual specificity mitogen-activated protein kinase kinase 1;ERK activator kinase 1;MAPK/ERK kinase 1;MAPKK 1;MEK 1;protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1) |
Product List
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Magic™ Human MEK1 U2OS Cell Line with pLuc Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX174]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MEK1 Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
mProX™ Human MAP2K1 Stable Cell Line
[CAT#: S01YF-1123-KX287]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MAP2K1 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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