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LILRB1

The leukocyte immunoglobulin-like receptor (LIR) family includes this gene. The encoded protein is a member of the LIR receptor subfamily B class, which has two to four extracellular immunoglobulin domains, one transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is found in immune cells, where it interacts with MHC class I molecules on antigen-presenting cells to provide a signal that prevents the initiation of an immune response. To assist focus the immune response and reduce autoreactivity, it is believed to control inflammatory reactions and cytotoxicity.

Full Name Leukocyte immunoglobulin like receptor B1
Gene ID Human: 10859
Rat: 100912456
Monkey: 692340
UniProt ID Human: Q8NHL6
Rat: A0A0G2JYU1
Monkey: F7H3G7
Alternative Names LILRB1; ILT2; LIR1; MIR7; PIRB; CD85J; ILT-2; LIR-1; MIR-7; PIR-B; leukocyte immunoglobulin-like receptor subfamily B member 1; CD85 antigen-like family member J; Ig-like transcript 2; immunoglobulin heavy chain variable region; leucocyte Ig-like receptor B1; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1; monocyte/macrophage immunoglobulin-like receptor 7; myeloid inhibitory receptor 7; Leukocyte immunoglobulin like receptor B1

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Product Category:
Membrane Protein Stable Cell Lines
Target Family: Oncology Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;THP-1
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