KRAS
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.
| Full Name | KRAS proto-oncogene, GTPase |
| Gene ID | Human: 3845 Mouse: 16653 Rat: 24525 Monkey: 707977 |
| UniProt ID | Human: P01116 Mouse: P32883 Rat: P08644 Monkey: F6VGN0 |
| Alternative Names | NS; NS3; OES; CFC2; RALD; K-Ras; KRAS1; KRAS2; RASK2; KI-RAS; C-K-RAS; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; K-Ras 2; 'C-K-RAS; c-Ki-ras; c-Ki-ras2; GTPase KRas; K-ras p21 protein; Kirsten rat sarcoma viral oncogene homolog; Kirsten rat sarcoma viral proto-oncogene; PR310 c-K-ras oncogene; c-Kirsten-ras protein; cellular c-Ki-ras2 proto-oncogene; cellular transforming proto-oncogene; oncogene KRAS2; proto-oncogene GTPase; transforming protein p21; v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog |
Product List
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Magic™ Human Kras (G12A) NCI-H1975 Cell Line with mNeonGreen Reporter
[CAT#: S01YF-0424-KX46]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: Kras (G12A) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: NCI-H1975 Assay Types: Functional assay
Magic™ Human KRAS (G12C) BaF3 Cell Line
[CAT#: S01YF-1222-KX767]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G12C) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human KRAS (G12C) NIH3T3 Cell Line
[CAT#: S01YF-1222-KX722]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G12C) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: NIH3T3 Assay Types: Drug screening and biological assays
Magic™ Human KRAS (G12C, A59S) BaF3 Cell Line
[CAT#: S01YF-1222-KX568]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G12C, A59S) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human KRAS (G12C, A59T) BaF3 Cell Line
[CAT#: S01YF-1222-KX567]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G12C, A59T) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human KRAS (G12C, H95D) BaF3 Cell Line
[CAT#: S01YF-1222-KX608]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G12C, H95D) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human KRAS (G12C, H95Q) BaF3 Cell Line
[CAT#: S01YF-1222-KX609]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G12C, H95Q) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human KRAS (G12C, H95R) BaF3 Cell Line
[CAT#: S01YF-0324-KX201]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G12C, H95R) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Magic™ Human KRAS (G12C, Q99L) BaF3 Cell Line
[CAT#: S01YF-1222-KX570]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G12C, Q99L) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human KRAS (G12C, R68M) BaF3 Cell Line
[CAT#: S01YF-1222-KX566]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G12C, R68M) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human KRAS (G12C, R68S) BaF3 Cell Line
[CAT#: S01YF-0324-KX202]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G12C, R68S) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Magic™ Human KRAS (G12C, Y96C) BaF3 Cell Line
[CAT#: S01YF-0324-KX203]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G12C, Y96C) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Magic™ Human KRAS (G12C, Y96D) BaF3 Cell Line
[CAT#: S01YF-0324-KX204]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G12C, Y96D) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Magic™ Human KRAS (G12C, Y96S) BaF3 Cell Line
[CAT#: S01YF-0324-KX205]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G12C, Y96S) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Magic™ Human KRAS (G12C/F) BaF3 Cell Line
[CAT#: S01YF-1222-KX622]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G12C/F) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human KRAS (G12D) BaF3 Cell Line
[CAT#: S01YF-1222-KX768]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G12D) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human Kras (G12D) NCI-H1975 Cell Line with EGFP Reporter
[CAT#: S01YF-0424-KX41]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: Kras (G12D) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: NCI-H1975 Assay Types: Functional assay
Magic™ Human Kras (G12D) NCI-H1975 Cell Line with mNeonGreen Reporter
[CAT#: S01YF-0424-KX44]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: Kras (G12D) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: NCI-H1975 Assay Types: Functional assay
Magic™ Human KRAS (G12L) BaF3 Cell Line
[CAT#: S01YF-1222-KX620]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G12L) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human KRAS (G12R) BaF3 Cell Line
[CAT#: S01YF-1222-KX621]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G12R) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human KRAS (G12V) BaF3 Cell Line
[CAT#: S01YF-1222-KX765]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G12V) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human Kras (G12V) NCI-H1975 Cell Line with EGFP Reporter
[CAT#: S01YF-0424-KX42]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: Kras (G12V) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: NCI-H1975 Assay Types: Functional assay
Magic™ Human Kras (G12V) NCI-H1975 Cell Line with mNeonGreen Reporter
[CAT#: S01YF-0424-KX45]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: Kras (G12V) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: NCI-H1975 Assay Types: Functional assay
Magic™ Human KRAS (G13C) BaF3 Cell Line
[CAT#: S01YF-1222-KX709]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G13C) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human KRAS (G13D) BaF3 Cell Line
[CAT#: S01YF-1222-KX714]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G13D) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human KRAS (G13E) BaF3 Cell Line
[CAT#: S01YF-1222-KX713]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G13E) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human KRAS (G13R) BaF3 Cell Line
[CAT#: S01YF-1222-KX711]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (G13R) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human KRAS (Q61K) BaF3 Cell Line
[CAT#: S01YF-1222-KX755]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KRAS (Q61K) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human Kras NCI-H1975 Cell Line with EGFP Reporter
[CAT#: S01YF-0424-KX39]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: Kras Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: NCI-H1975 Assay Types: Functional assay
Magic™ Human Kras (G12A) NCI-H1975 Cell Line with EGFP Reporter
[CAT#: S01YF-0424-KX43]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: Kras (G12A) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: NCI-H1975 Assay Types: Functional assay
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