IL3RA
The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.
| Full Name | Interleukin 3 receptor subunit alpha |
| Gene ID | Human: 3563 Mouse: 16188 Rat: 246144 Monkey: 106995138 |
| UniProt ID | Human: P26951 Mouse: P26952 Rat: E9PSX4 Monkey: A0A5F7ZI63 |
| Alternative Names | IL3RA; IL3R; CD123; IL3RX; IL3RY; IL3RAY; hIL-3Ra; CD123 antigen; IL-3 receptor subunit alpha; IL-3R subunit alpha; IL-3R-alpha; IL-3RA; interleukin 3 receptor, alpha (low affinity); Interleukin 3 receptor subunit alpha |
Product List
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- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: IL3RA Target Family: Immune Checkpoint Target Protein Species: Cyno Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: IL3RA Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: C1498 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: IL3RA Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CT26 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: IL3RA Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: IL3RA Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;HAECs Assay Types: Biological assays
