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HCRTR1

This gene encodes a protein that is a G-protein coupled receptor that controls eating behavior. The hypothalamic neuropeptide orexin A is preferentially bound by the encoded protein. Orexin A and orexin B are bound by a G-protein coupled receptor that is encoded by the homologous gene HCRTR2. Among the illnesses linked to HCRTR1 are Rohhad and Narcolepsy. Orexin, neuropeptides FF and QRFP, which bind to their respective receptors and Class A, are among its linked pathways. This gene has annotations for G protein-coupled receptor function and peptide hormone binding in the Gene Ontology (GO) database.

Full Name Hypocretin receptor 1
Gene ID Human: 3061
Mouse: 230777
Rat: 25593
Monkey: 705914
UniProt ID Human: O43613
Mouse: P58307
Rat: P56718
Monkey: A0A2K5VL06
Alternative Names OX1R; orexin receptor type 1; hypocretin (orexin) receptor 1; hypocretin receptor type 1; orexin receptor 1; HCRTR1; Hypocretin receptor 1

Product List

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: HCRTR1 Target Family: Orexin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: HCRTR1 Target Family: Orexin Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: HCRTR1 Target Family: Orexin Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: HCRTR1 Target Family: Orexin Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: HCRTR1 Target Family: Orexin receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: HCRTR1 Target Family: Orexin Receptor Target Protein Species: Mouse Host Cell Type: CHO-K1 Assay Types: Calcium Flux Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: HCRTR1 Target Family: Orexin Receptors Target Protein Species: Human
Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: HCRTR1 Target Family: Orexin Receptor Target Protein Species: Rat Host Cell Type: CHO-K1 Assay Types: Calcium Flux Assay
Magic™ Rat HCRTR1 IP1 Assay [CAT#: S01YF-1122-KX754]

Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: HCRTR1 Target Family: Orexin Receptor Target Protein Species: Rat Host Cell Type: CHO-K1 Assay Types: IP1 Assay
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