HCRTR1
This gene encodes a protein that is a G-protein coupled receptor that controls eating behavior. The hypothalamic neuropeptide orexin A is preferentially bound by the encoded protein. Orexin A and orexin B are bound by a G-protein coupled receptor that is encoded by the homologous gene HCRTR2. Among the illnesses linked to HCRTR1 are Rohhad and Narcolepsy. Orexin, neuropeptides FF and QRFP, which bind to their respective receptors and Class A, are among its linked pathways. This gene has annotations for G protein-coupled receptor function and peptide hormone binding in the Gene Ontology (GO) database.
| Full Name | Hypocretin receptor 1 |
| Gene ID | Human: 3061 Mouse: 230777 Rat: 25593 Monkey: 705914 |
| UniProt ID | Human: O43613 Mouse: P58307 Rat: P56718 Monkey: A0A2K5VL06 |
| Alternative Names | OX1R; orexin receptor type 1; hypocretin (orexin) receptor 1; hypocretin receptor type 1; orexin receptor 1; HCRTR1; Hypocretin receptor 1 |
Product List
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Magic™ Human FLAG tagged HCRTR1 CHO-K1 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX507]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HCRTR1 Target Family: Orexin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human HCRTR1 (NM_001521.1) CHO-K1 Membrane Preparation
[CAT#: S01YF-0722-KX805]
- Product Category:
- Membranes
- Target Protein: OX1 Target Family: Orexin Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human HCRTR1 Chem-1 Cell Line, Calcium flux assay
[CAT#: S01YF-0822-KX750]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HCRTR1 Target Family: Orexin Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: Chem-1 Assay Types: Calcium flux assay
Magic™ Human HCRTR1 CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay
[CAT#: S01YF-1222-KX193]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HCRTR1 Target Family: Orexin Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human HCRTR1 CHO-K1 Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay
[CAT#: S01YF-1222-KX102]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HCRTR1 Target Family: Orexin Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
Magic™ Human HCRTR1 CHO-K1 Cell Line, Binding and Functional Assay
[CAT#: S01YF-1222-KX201]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HCRTR1 Target Family: Orexin Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
Magic™ Human HCRTR1 CHO-K1 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX89]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HCRTR1 Target Family: Orexin receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human HCRTR1 CHO-K1 Cell Line, β-arrestin assay
[CAT#: S01YF-0822-KX521]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HCRTR1 Target Family: Orexin Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
Magic™ Human HCRTR1 CHO-K1 Membrane Preparation
[CAT#: S01YF-0722-KX429]
- Product Category:
- Membranes
- Target Protein: OX1 Target Family: Orexin Target Protein Species: Human Host Cell Type: CHO-K1 Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human HCRTR1 U2OS Cell Line, Internalization assay
[CAT#: S01YF-0822-KX522]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HCRTR1 Target Family: Orexin Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: U2OS Assay Types: Internalization assay
Magic™ Mouse HCRTR1 Calcium Flux Assay
[CAT#: S01YF-1122-KX752]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: HCRTR1 Target Family: Orexin Receptor Target Protein Species: Mouse Host Cell Type: CHO-K1 Assay Types: Calcium Flux Assay
Magic™ mPro Human HCRTR1 Cell Line
[CAT#: S01YF-1122-KX44]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: HCRTR1 Target Family: Orexin Receptors Target Protein Species: Human
Magic™ Rat HCRTR1 Calcium Flux Assay
[CAT#: S01YF-1122-KX753]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: HCRTR1 Target Family: Orexin Receptor Target Protein Species: Rat Host Cell Type: CHO-K1 Assay Types: Calcium Flux Assay
Magic™ Rat HCRTR1 IP1 Assay
[CAT#: S01YF-1122-KX754]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: HCRTR1 Target Family: Orexin Receptor Target Protein Species: Rat Host Cell Type: CHO-K1 Assay Types: IP1 Assay
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