HCRTR1
This gene encodes a protein that is a G-protein coupled receptor that controls eating behavior. The hypothalamic neuropeptide orexin A is preferentially bound by the encoded protein. Orexin A and orexin B are bound by a G-protein coupled receptor that is encoded by the homologous gene HCRTR2. Among the illnesses linked to HCRTR1 are Rohhad and Narcolepsy. Orexin, neuropeptides FF and QRFP, which bind to their respective receptors and Class A, are among its linked pathways. This gene has annotations for G protein-coupled receptor function and peptide hormone binding in the Gene Ontology (GO) database.
Full Name | Hypocretin receptor 1 |
Gene ID | Human: 3061 Mouse: 230777 Rat: 25593 Monkey: 705914 |
UniProt ID | Human: O43613 Mouse: P58307 Rat: P56718 Monkey: A0A2K5VL06 |
Alternative Names | OX1R; orexin receptor type 1; hypocretin (orexin) receptor 1; hypocretin receptor type 1; orexin receptor 1; HCRTR1; Hypocretin receptor 1 |
Product List
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: HCRTR1 Target Family: Orexin Receptor Target Protein Species: Mouse Host Cell Type: CHO-K1 Assay Types: Calcium Flux Assay
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: HCRTR1 Target Family: Orexin Receptor Target Protein Species: Rat Host Cell Type: CHO-K1 Assay Types: Calcium Flux Assay
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: HCRTR1 Target Family: Orexin Receptor Target Protein Species: Rat Host Cell Type: CHO-K1 Assay Types: IP1 Assay