GUCY2C
This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive).
Full Name | Guanylate cyclase 2C |
Gene ID | Human: 2984 Mouse: 14917 Rat: 25711 Monkey: 699191 |
UniProt ID | Human: P25092 Mouse: Q3UWA6 Rat: P23897 Monkey: A0A5F8ATF2 |
Alternative Names | GUCY2C; GC-C; STAR; DIAR6; GUC2C; MECIL; MUCIL; heat-stable enterotoxin receptor; STA receptor; guanylyl cyclase C; intestinal guanylate cyclase; Guanylate cyclase 2C |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;MIN6