GRM1
A metabotropic glutamate receptor that is encoded by this gene works by turning on phospholipase C. The central nervous system's main excitatory neurotransmitter, L-glutamate, activates both ionotropic and metabotropic glutamate receptors. Most parts of normal brain function entail glutamatergic neurotransmission, which can be disturbed by a variety of neuropathologic disorders. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer, and the phosphatidylinositol-calcium second messenger system, which is related to G proteins, regulates its activity. Numerous illness conditions, such as schizophrenia, bipolar disorder, depression, and breast cancer, may be linked to this gene.
| Full Name | Glutamate metabotropic receptor 1 |
| Gene ID | Human: 2911 Mouse: 14816 Rat: 24414 Monkey: 698736 |
| UniProt ID | Human: Q13255 Mouse: P97772 Rat: P23385 Monkey: Q0QDS2 |
| Alternative Names | MGLU1; SCA44; GPRC1A; MGLUR1; SCAR13; PPP1R85; glutamate receptor, metabotropic 1; protein phosphatase 1, regulatory subunit 85; GRM1; Glutamate metabotropic receptor 1 |
Product List
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Magic™ Human FLAG tagged GRM1 CHO-K1 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX436]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRM1 Target Family: Metabotropic Glutamate Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
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