GRK2
This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease.
| Full Name | G protein-coupled receptor kinase 2 |
| Gene ID | Human: 156 Mouse: 110355 Rat: 25238 Monkey: 721754 |
| UniProt ID | Human: P25098 Mouse: Q99MK8 Rat: P26817 |
| Alternative Names | BARK1; ADRBK1; BETA-ARK1;beta-adrenergic receptor kinase 1;adrenergic beta receptor kinase 1;beta-ARK-1 |
Product List
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mProX™ Human GRK2 Stable Cell Line
[CAT#: S01YF-1123-KX155]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GRK2 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: UW228-2; CHO-K1; HEK293
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