GPR52
Through modulating dopamine, NMDA, and ADORA2A-induced locomotor activity, GPR52 may contribute to locomotor activity. The striatal dopamine receptor signaling system is altered along with these behavioral alterations. the activation of RAB39B, which translocates HTT to the endoplasmic reticulum and modifies HTT level via cAMP-dependent but PKA independent processes, prevents proteasome degradation of HTT.
| Full Name | G protein-coupled receptor 52 |
| Gene ID | Human: 9293 Mouse: 620246 Rat: 684623 Monkey: 708279 |
| UniProt ID | Human: Q9Y2T5 Mouse: P0C5J4 Rat: Q9WU09 Monkey: A0A2K5BXC1 |
| Alternative Names | G-protein coupled receptor 52; probable G-protein coupled receptor 52; GPR52; G protein-coupled receptor 52 |
Product List
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Magic™ Human FLAG tagged GPR52 & ARRB2 HEK293T β-Arrestin2 Cell Line, β-Arrestin Assay
[CAT#: S01YF-1022-KX523]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR52; ARRB2 Target Family: Orphan Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T β-Arrestin2 Assay Types: β-Arrestin Assay
Magic™ Human FLAG tagged GPR52 HEK293T Cell Line, cAMP assay
[CAT#: S01YF-1022-KX522]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR52 Target Family: Orphan Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: cAMP assay
Magic™ Human GPR52 (NM_005684) HEK293T Membrane Preparation
[CAT#: S01YF-0722-KX820]
- Product Category:
- Membranes
- Target Protein: GPR52 Target Family: Orphan Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human GPR52 and ARRB2 (NM_005684 and NM_004313.3) HEK293T β-Arrestin2 Membrane Preparation
[CAT#: S01YF-0722-KX821]
- Product Category:
- Membranes
- Target Protein: GPR52 Target Family: Orphan Target Protein Species: Human Protein Tag: FLAG tag at N-terminus Host Cell Type: HEK293T β-Arrestin2 Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human GPR52 CHO-K1 Cell Line, β-arrestin assay
[CAT#: S01YF-0822-KX483]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR52 Target Family: Class A Orphan Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
Magic™ Human GPR52 U2OS Cell Line, β-arrestin assay
[CAT#: S01YF-0822-KX484]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR52 Target Family: Class A Orphan Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: U2OS Assay Types: β-arrestin assay
Magic™ Mouse GPR52 cAMP Assay
[CAT#: S01YF-1122-KX787]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: GPR52 Target Family: Orphan Receptor Target Protein Species: Mouse Host Cell Type: CHO-K1 Assay Types: cAMP Assay
Magic™ Rat GPR52 cAMP Assay
[CAT#: S01YF-1122-KX788]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: GPR52 Target Family: Orphan Receptor Target Protein Species: Rat Host Cell Type: CHO-K1 Assay Types: cAMP Assay
mProX™ Human GPR52 Stable Cell Line
[CAT#: S01YF-0923-PY167]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR52 Target Family: Orphan Family Target Protein Species: Human Host Cell Type: HepG2;CHO-K1;HEK293 Assay Types: Biological assays
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