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GPR52

Through modulating dopamine, NMDA, and ADORA2A-induced locomotor activity, GPR52 may contribute to locomotor activity. The striatal dopamine receptor signaling system is altered along with these behavioral alterations. the activation of RAB39B, which translocates HTT to the endoplasmic reticulum and modifies HTT level via cAMP-dependent but PKA independent processes, prevents proteasome degradation of HTT.

Full Name G protein-coupled receptor 52
Gene ID Human: 9293
Mouse: 620246
Rat: 684623
Monkey: 708279
UniProt ID Human: Q9Y2T5
Mouse: P0C5J4
Rat: Q9WU09
Monkey: A0A2K5BXC1
Alternative Names G-protein coupled receptor 52; probable G-protein coupled receptor 52; GPR52; G protein-coupled receptor 52

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR52; ARRB2 Target Family: Orphan Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T β-Arrestin2 Assay Types: β-Arrestin Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR52 Target Family: Orphan Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: cAMP assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR52 Target Family: Orphan Family Target Protein Species: Human Host Cell Type: HepG2;CHO-K1;HEK293
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