GPR52
Through modulating dopamine, NMDA, and ADORA2A-induced locomotor activity, GPR52 may contribute to locomotor activity. The striatal dopamine receptor signaling system is altered along with these behavioral alterations. the activation of RAB39B, which translocates HTT to the endoplasmic reticulum and modifies HTT level via cAMP-dependent but PKA independent processes, prevents proteasome degradation of HTT.
| Full Name | G protein-coupled receptor 52 |
| Gene ID | Human: 9293 Mouse: 620246 Rat: 684623 Monkey: 708279 |
| UniProt ID | Human: Q9Y2T5 Mouse: P0C5J4 Rat: Q9WU09 Monkey: A0A2K5BXC1 |
| Alternative Names | G-protein coupled receptor 52; probable G-protein coupled receptor 52; GPR52; G protein-coupled receptor 52 |
Product List
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Magic™ Human FLAG tagged GPR52 HEK293T Cell Line, cAMP assay
[CAT#: S01YF-1022-KX522]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR52 Target Family: Orphan Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: cAMP assay
mProX™ Human GPR52 Stable Cell Line
[CAT#: S01YF-0923-PY167]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR52 Target Family: Orphan Family Target Protein Species: Human Host Cell Type: HepG2;CHO-K1;HEK293
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