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GPR119

The pancreas and gastrointestinal tract both express a G-protein-coupled receptor that is a member of the rhodopsin subfamily. The encoded protein may play a role in glucose homeostasis as it is triggered by lipid amides such lysophosphatidylcholine and oleoylethanolamide. A possible therapeutic target for the treatment of type 2 diabetes is this protein. G proteins, which trigger adenylate cyclase, control the activation of this receptor.

Full Name G protein-coupled receptor 119
Gene ID Human: 139760
Mouse: 236781
Rat: 302813
Monkey: 703368
UniProt ID Human: Q8TDV5
Mouse: Q7TQP3
Rat: Q7TQN8
Monkey: F7HMG7
Alternative Names GPCR2; glucose-dependent insulinotropic receptor; G-protein coupled receptor 2; GPR119; G protein-coupled receptor 119

Product List

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR119 Target Family: Free Fatty Acid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: cAMP assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR119 Target Family: Free Fatty Acid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: cAMP assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR119 Target Family: Orphan Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR119 Target Family: Orphan Receptors Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR119 Target Family: Free Fatty Acid Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR119 Target Family: Free Fatty Acid Target Protein Species: Mouse Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: cAMP assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR119 Target Family: Class A Orphan Receptors Target Protein Species: Human
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR119 Target Family: Free Fatty Acid Family Target Protein Species: Mouse Host Cell Type: GLUTag;CHO-K1;HEK293
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