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GABBR1

Gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the mammalian central nervous system, is encoded by this gene as a receptor. This receptor and GABA(B) receptor 2 work together as a heterodimer. Epilepsy and schizophrenia may both be caused by defects in this gene. GPCR downstream signaling and sensory perception of taste are two of its linked pathways. G protein-coupled receptor activity and G protein-coupled GABA receptor activity are two Gene Ontology (GO) annotations associated with this gene.

Full Name Gamma-aminobutyric acid type B receptor subunit 1
Gene ID Human: 2550
Mouse: 54393
Rat: 81657
Monkey: 708987
UniProt ID Human: Q9UBS5
Mouse: Q9WV18
Rat: Q9Z0U4
Monkey: A0A0D9R6U4
Alternative Names GB1; GPRC3A; GABABR1; GABBR1-3; GABA-B receptor, R1 subunit; gamma-aminobutyric acid (GABA) B receptor, 1; seven transmembrane helix receptor; GABBR1; Gamma-aminobutyric acid type B receptor subunit 1

Product List

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Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: GABBR1a/GABBR2 Target Family: GABA Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: cAMP Assay
Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: GABBR1a/GABBR2 Target Family: GABA Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Radioligand Binding Assay
Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: GABBR1b/GABBR2 Target Family: GABA Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: cAMP Assay
Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: GABBR1a/GABBR2 Target Family: GABA Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: [35S]GTPγS binding Assay
Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: GABBR1a/GABBR2 Target Family: GABA Target Protein Species: Human Host Cell Type: CHO-K1-Gα16 Assay Types: Calcium Flux Assay
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