GABBR1
Gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the mammalian central nervous system, is encoded by this gene as a receptor. This receptor and GABA(B) receptor 2 work together as a heterodimer. Epilepsy and schizophrenia may both be caused by defects in this gene. GPCR downstream signaling and sensory perception of taste are two of its linked pathways. G protein-coupled receptor activity and G protein-coupled GABA receptor activity are two Gene Ontology (GO) annotations associated with this gene.
| Full Name | Gamma-aminobutyric acid type B receptor subunit 1 |
| Gene ID | Human: 2550 Mouse: 54393 Rat: 81657 Monkey: 708987 |
| UniProt ID | Human: Q9UBS5 Mouse: Q9WV18 Rat: Q9Z0U4 Monkey: A0A0D9R6U4 |
| Alternative Names | GB1; GPRC3A; GABABR1; GABBR1-3; GABA-B receptor, R1 subunit; gamma-aminobutyric acid (GABA) B receptor, 1; seven transmembrane helix receptor; GABBR1; Gamma-aminobutyric acid type B receptor subunit 1 |
Product List
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Magic™ Human GABBR1a/GABBR2 [35S]GTPγS binding Assay
[CAT#: S01YF-1122-KX474]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: GABBR1a/GABBR2 Target Family: GABA Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: [35S]GTPγS binding Assay
Magic™ Human GABBR1a/GABBR2 Calcium Flux Assay
[CAT#: S01YF-1122-KX472]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: GABBR1a/GABBR2 Target Family: GABA Target Protein Species: Human Host Cell Type: CHO-K1-Gα16 Assay Types: Calcium Flux Assay
Magic™ Human GABBR1a/GABBR2 cAMP Assay
[CAT#: S01YF-1122-KX473]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: GABBR1a/GABBR2 Target Family: GABA Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: cAMP Assay
Magic™ Human GABBR1a/GABBR2 Radioligand Binding Assay
[CAT#: S01YF-1122-KX475]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: GABBR1a/GABBR2 Target Family: GABA Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Radioligand Binding Assay
Magic™ Human GABBR1b/GABBR2 cAMP Assay
[CAT#: S01YF-1122-KX476]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: GABBR1b/GABBR2 Target Family: GABA Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: cAMP Assay
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