GABBR1
Gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the mammalian central nervous system, is encoded by this gene as a receptor. This receptor and GABA(B) receptor 2 work together as a heterodimer. Epilepsy and schizophrenia may both be caused by defects in this gene. GPCR downstream signaling and sensory perception of taste are two of its linked pathways. G protein-coupled receptor activity and G protein-coupled GABA receptor activity are two Gene Ontology (GO) annotations associated with this gene.
Full Name | Gamma-aminobutyric acid type B receptor subunit 1 |
Gene ID | Human: 2550 Mouse: 54393 Rat: 81657 Monkey: 708987 |
UniProt ID | Human: Q9UBS5 Mouse: Q9WV18 Rat: Q9Z0U4 Monkey: A0A0D9R6U4 |
Alternative Names | GB1; GPRC3A; GABABR1; GABBR1-3; GABA-B receptor, R1 subunit; gamma-aminobutyric acid (GABA) B receptor, 1; seven transmembrane helix receptor; GABBR1; Gamma-aminobutyric acid type B receptor subunit 1 |
Product List
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: GABBR1a/GABBR2 Target Family: GABA Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: cAMP Assay
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: GABBR1a/GABBR2 Target Family: GABA Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Radioligand Binding Assay
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: GABBR1b/GABBR2 Target Family: GABA Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: cAMP Assay
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: GABBR1a/GABBR2 Target Family: GABA Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: [35S]GTPγS binding Assay
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: GABBR1a/GABBR2 Target Family: GABA Target Protein Species: Human Host Cell Type: CHO-K1-Gα16 Assay Types: Calcium Flux Assay