FAP
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Full Name | Fibroblast activation protein alpha |
| Gene ID | Human: 2191 Mouse: 14089 Rat: 192203 Monkey: 701541 |
| UniProt ID | Human: Q12884 Mouse: P97321 |
| Alternative Names | FAP; FAPA; SIMP; DPPIV; FAPalpha; prolyl endopeptidase FAP; 170 kDa melanoma membrane-bound gelatinase; dipeptidyl peptidase FAP; gelatine degradation protease FAP; integral membrane serine protease; post-proline cleaving enzyme; seprase; surface-expressed protease; Fibroblast activation protein alpha |
Product List
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mProX™ Human FAP Stable Cell Line
[CAT#: S01YF-1023-PY268]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Other Targets Target Protein Species: Human Host Cell Type: HEK293;CHO-K1KB
Human FAP Membrane Protein Yeast Expression Plasmid
[CAT#: S01YF-1124-KX623]
- Product Category:
- Membrane Protein Tools
- Target Protein: FAP Target Family: Others Vector: pYE Vector Type: Yeast Expression Vector
Human FAP Membrane Protein Retroviral Expression Plasmid
[CAT#: S01YF-1124-KX968]
- Product Category:
- Membrane Protein Tools
- Target Protein: FAP Target Family: Others Vector: pRV Vector Type: Retroviral Expression Vector
Human FAP Membrane Protein Mammalian Transient Expression Plasmid
[CAT#: S01YF-1124-KX393]
- Product Category:
- Membrane Protein Tools
- Target Protein: FAP Target Family: Others Vector: pME Vector Type: Mammalian Transient Expression Vector
Human FAP Membrane Protein LNP Encapsulation mRNA
[CAT#: S01YF-1124-KX278]
- Product Category:
- Membrane Protein Tools
- Target Protein: FAP Target Family: Others RNA Type: LNP-mRNA Formation: LNP Encapsulation mRNA
Human FAP Membrane Protein Lentivirus
[CAT#: S01YF-1124-KX48]
- Product Category:
- Membrane Protein Tools
- Target Protein: FAP Target Family: Others
Human FAP Membrane Protein Lentiviral Expression Plasmid
[CAT#: S01YF-1124-KX853]
- Product Category:
- Membrane Protein Tools
- Target Protein: FAP Target Family: Others Vector: pLV Vector Type: Lentiviral Expression Vector
Human FAP Membrane Protein Insect Expression Plasmid
[CAT#: S01YF-1124-KX508]
- Product Category:
- Membrane Protein Tools
- Target Protein: FAP Target Family: Others Vector: pIE Vector Type: Insect Expression Vector
Human FAP Membrane Protein In Vitro Transcription (IVT) mRNA
[CAT#: S01YF-1124-KX163]
- Product Category:
- Membrane Protein Tools
- Target Protein: FAP Target Family: Others RNA Type: IVT mRNA Formation: In Vitro Transcription (IVT) mRNA
Human FAP Membrane Protein Bacterial Expression Plasmid
[CAT#: S01YF-1124-KX738]
- Product Category:
- Membrane Protein Tools
- Target Protein: FAP Target Family: Others Vector: pBE Vector Type: Bacterial Expression Vector
Human FAP Membrane Protein In Vitro Transcription (IVT) Plasmid
[CAT#: S01YF-1124-KX1083]
- Product Category:
- Membrane Protein Tools
- Target Protein: FAP Target Family: Others Vector: pIVT Vector Type: In Vitro Transcription (IVT) Vector
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