FAP
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Full Name | Fibroblast activation protein alpha |
| Gene ID | Human: 2191 Mouse: 14089 Rat: 192203 Monkey: 701541 |
| UniProt ID | Human: Q12884 Mouse: P97321 |
| Alternative Names | FAP; FAPA; SIMP; DPPIV; FAPalpha; prolyl endopeptidase FAP; 170 kDa melanoma membrane-bound gelatinase; dipeptidyl peptidase FAP; gelatine degradation protease FAP; integral membrane serine protease; post-proline cleaving enzyme; seprase; surface-expressed protease; Fibroblast activation protein alpha |
Product List
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Magic™ Human FAP 4T1 Cell Line
[CAT#: S01YF-0324-KX26]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FAP Target Family: Others Target Protein Species: Human Host Cell Type: 4T1 Assay Types: Functional assay and biological assay
Magic™ Human FAP B16F10 Cell Line
[CAT#: S01YF-0324-KX37]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FAP Target Family: Others Target Protein Species: Human Host Cell Type: B16F10 Assay Types: Functional assay and biological assay
Magic™ Human FAP CT26 Cell Line
[CAT#: S01YF-0324-KX53]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FAP Target Family: Others Target Protein Species: Human Host Cell Type: CT26 Assay Types: Functional assay and biological assay
Magic™ Human FAP HEK293T Cell Line
[CAT#: S01YF-0123-KX191]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FAP Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Human FAP HT1080 Cell Line
[CAT#: S01YF-0123-KX34]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FAP Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HT1080 Assay Types: Drug screening and biological assays
Magic™ Human FAP MC-38 Cell Line
[CAT#: S01YF-0324-KX110]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FAP Target Family: Others Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
Magic™ Human FAP WEHI 164 Cell Line
[CAT#: S01YF-0324-KX139]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FAP Target Family: Others Target Protein Species: Human Host Cell Type: WEHI 164 Assay Types: Functional assay and biological assay
Magic™ Mouse FAP NIH3T3 Cell Line
[CAT#: S01YF-0123-KX96]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FAP Target Family: Others Target Protein Species: Mouse Protein Tag: Tag-free Host Cell Type: NIH3T3 Assay Types: Drug screening and biological assays
mProX™ Human FAP Stable Cell Line
[CAT#: S01YF-1023-PY268]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Other Targets Target Protein Species: Human Host Cell Type: HEK293;CHO-K1KB
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