EPOR
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
| Full Name | Erythropoietin receptor |
| Gene ID | Human: 2057 Mouse: 13857 Rat: 24336 Monkey: 714546 |
| UniProt ID | Human: P19235 Mouse: P14753 Rat: Q07303 Monkey: F7GNY3 |
| Alternative Names | EPOR; EPO-R; truncated erythropoietin receptor; Erythropoietin receptor |
Product List
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Magic™ Human EPOR BaF3 Cell Line
[CAT#: S01YF-1222-KX707]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EPOR Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
mProX™ Human EPOR Stable Cell Line
[CAT#: S01YF-1023-PY149]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;UT-7;A2780;H1299
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