EPCAM
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
Full Name | Epithelial cell adhesion molecule |
Gene ID | Human: 4072 Mouse: 17075 Rat: 171577 Monkey: 677680 |
UniProt ID | Human: P16422 Mouse: Q99JW5 Rat: O55159 Monkey: F7EB13 |
Alternative Names | EPCAM; ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1; adenocarcinoma-associated antigen; cell surface glycoprotein Trop-1; epithelial glycoprotein 314; human epithelial glycoprotein-2; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein); trophoblast cell surface antigen 1; tumor-associated calcium signal transducer 1; Epithelial cell adhesion molecule |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;MCF-7;MDA-MB-231
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EPCAM Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: ID8 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EPCAM Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EPCAM Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CT26 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EPCAM Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: MC-38 Assay Types: Drug screening and biological assays