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EML4

This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants.

Full Name EMAP like 4
Gene ID Human: 27436 Mouse: 78798 Rat: 313861 Monkey: 715091
UniProt ID Human: Q9HC35 Mouse: Q3UMY5
Alternative Names C2orf2; ELP120; EMAP-4; EMAPL4; ROPP120;echinoderm microtubule-associated protein-like 4;echinoderm microtubule associated protein like 4;restrictedly overexpressed proliferation-associated protein;ropp 120

Product List

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (L1196M/L1198F) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (L1198F) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (S1206F) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (T1151Tins) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (V1180L) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (C1156Y, G1202R) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (C1156Y, L1198F) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (D1203N) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (D1203N, E1210K) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (D1203N, F1174C) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (E1210K) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (F1174C) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (F1174L) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (G1202Del) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (G1202R) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (G1202R, G1269A) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (G1202R, G1269A, L1198F) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (G1202R, G1269A, L1204V) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (G1202R, L1196M) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (G1202R, L1198F) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (G1202R/L1198F) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (C1156Y) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (G1269A) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (G1269S) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (I1171N) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (I1171N, F1174I) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (I1171N, L1198H) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (I1171S) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (I1171T) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: EML4 & ALK (L1196M) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
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