CXCR6
This gene encodes a G protein-coupled receptor that is a member of the CXC chemokine receptor family. It has seven transmembrane domains. The bone marrow stromal cells and various T lymphocyte subsets express this gene, which maps to the chemokine receptor gene cluster. The encoded protein and chemokine ligand 16 (CCL16), which is its sole ligand, are a component of a signaling system that controls T lymphocyte migration to different peripheral tissues and fosters cell-cell contact with dendritic cells and fibroblastic reticular cells. Additionally, CXCR6/CCL16 regulates resident memory T cell localization to various lung compartments and maintains resident memory T lymphocytes in the airways, which serve as an essential initial line of defense against respiratory infections.
| Full Name | C-X-C motif chemokine receptor 6 |
| Gene ID | Human: 10663 Mouse: 80901 Rat: 100124593 Monkey: 713829 |
| UniProt ID | Human: O00574 Mouse: Q9EQ16 Rat: A7ISD5 Monkey: Q9XT45 |
| Alternative Names | BONZO; CD186; CDw186; STRL33; TYMSTR; C-X-C chemokine receptor type 6; G protein-coupled receptor; G-protein coupled receptor STRL33; G-protein coupled receptor bonzo; chemokine (C-X-C motif) receptor 6; CXCR6; C-X-C motif chemokine receptor 6 |
Product List
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- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CXCR6 Target Family: Chemokine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CXCR6 Target Family: Chemokine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CXCR6 Target Family: Chemokine Receptor Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CXCR6 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: cAMP assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CXCR6 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: cAMP assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CXCR6 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Gαqi5 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CXCR6 Target Family: Chemokine Family Target Protein Species: Human Host Cell Type: HGC-27;CHO-K1;HEK293
