CDH3
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS).
| Full Name | Cadherin 3 |
| Gene ID | Human: 1001 Mouse: 12560 Rat: 116777 Monkey: 102142204 |
| UniProt ID | Human: P22223 Mouse: P10287 Rat: F1LMI3 Monkey: F6RPA3 |
| Alternative Names | CDH3; CDHP; HJMD; PCAD; cadherin-3; cadherin 3, type 1, P-cadherin (placental); calcium-dependent adhesion protein, placental; Cadherin 3 |
Product List
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- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CDH3 Target Family: Oncology Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
