CDH17
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.
| Full Name | Cadherin 17 |
| Gene ID | Human: 1015 Mouse: 12557 Rat: 117048 Monkey: 102129651 |
| UniProt ID | Human: Q12864 Mouse: Q9R100 Rat: P55281 Monkey: A0A1D5R2B4 |
| Alternative Names | HPT1; CDH16; HPT-1; cadherin-17; HPT-1 cadherin; LI cadherin; cadherin 17, LI cadherin (liver-intestine); cadherin-16; human intestinal peptide-associated transporter HPT-1; human peptide transporter 1; intestinal peptide-associated transporter HPT-1; liver-intestine cadherin; CDH17; Cadherin 17 |
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Magic™ Human CDH17 MC-38 Cell Line
[CAT#: S01YF-0324-KX5]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CDH17 Target Family: Oncology Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
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