CD70
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Full Name | CD70 molecule |
Gene ID | Human: 970 Mouse: 21948 Rat: 301132 Monkey: 701080 |
UniProt ID | Human: P32970 Mouse: O55237 Rat: M0R613 Monkey: F7GPA5 |
Alternative Names | CD70; CD27L; LPFS3; CD27-L; CD27LG; TNFSF7; TNLG8A; CD70 antigen; CD27 ligand; Ki-24 antigen; surface antigen CD70; tumor necrosis factor ligand 8A; tumor necrosis factor ligand superfamily member 7; CD70 molecule |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD70 Target Family: CD Target Protein Species: Cyno Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD70 Target Family: CD Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD70 Target Family: CD Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD70 Target Family: CD Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD70 Target Family: CD Target Protein Species: Mouse Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: CD Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;HCC44;H23