CASR
This gene encodes a protein that is a plasma membrane G protein-coupled receptor that detects minute variations in blood calcium levels. The encoded protein links this data to intracellular signaling pathways that change renal cation handling or parathyroid hormone release, and as a result, this protein is crucial for preserving mineral ion homeostasis. Familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia are all caused by mutations in this gene.
| Full Name | Calcium sensing receptor |
| Gene ID | Human: 846 Mouse: 12374 Rat: 24247 Monkey: 714441 |
| UniProt ID | Human: P41180 Mouse: Q9QY96 Rat: P48442 Monkey: F7B0G9 |
| Alternative Names | CAR; FHH; FIH; HHC; EIG8; HHC1; NSHPT; PCAR1; hCasR; GPRC2A; HYPOC1; extracellular calcium-sensing receptor; parathyroid Ca(2+)-sensing receptor 1; parathyroid cell calcium-sensing receptor 1; CASR; Calcium sensing receptor |
Product List
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Magic™ Human CaSR CHO-K1 Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay
[CAT#: S01YF-1222-KX26]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CaSR Target Family: Calcium-Sensing Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
Magic™ Human FLAG tagged CASR HEK293T Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX232]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CASR Target Family: Calcium-Sensing Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Magic™ Rat FLAG tagged CASR HEK293T Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX233]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CASR Target Family: Calcium-Sensing Target Protein Species: Rat Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
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