BMPR2
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.
| Full Name | bone morphogenetic protein receptor type 2 |
| Gene ID | Human: 659 Mouse: 12168 Rat: 140590 Monkey: 704088 |
| UniProt ID | Human: Q13873 Mouse: O35607 Rat: F1LQC5 |
| Alternative Names | BMR2; PPH1; BMPR3; BRK-3; POVD1; T-ALK; BMPR-II;bone morphogenetic protein receptor type-2;BMP type II receptor;BMP type-2 receptor;bone morphogenetic protein receptor type II;bone morphogenetic protein receptor, type II (serine/threonine kinase);type II activin receptor-like kinase;type II receptor for bone morphogenetic protein-4 |
Product List
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Magic™ Human BMPR2 Assay
[CAT#: S01YF-1122-KX1038]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: BMPR2 Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
mProX™ Human BMPR2 Stable Cell Line
[CAT#: S01YF-1123-KX159]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: BMPR2 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: INA-6; JJN-3; CHO-K1; HEK293
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