BCL2
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
Full Name | BCL2 apoptosis regulator |
Gene ID | Human: 596 Mouse: 12043 Rat: 24224 Monkey: 707407 |
UniProt ID | Human: P10415 Mouse: P10417 Rat: P49950 Monkey: A0A5F7ZZ15 |
Alternative Names | BCL2; Bcl-2; PPP1R50; apoptosis regulator Bcl-2; B-cell CLL/lymphoma 2; protein phosphatase 1, regulatory subunit 50; BCL2 apoptosis regulator |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: BCL2 (G101V) Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: RS411 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;H1975
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: BCL2 (F104L) Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: RS411 Assay Types: Drug screening and biological assays