ADRA1B
Among the conditions linked to ADRA1B are ureter, cancer of, and ureterolithiasis. Activation of cAMP-Dependent PKA and Monoamine GPCRs are two of its associated pathways. G protein-coupled receptor activity and alpha1-adrenergic receptor activity are two GO annotations for this gene. By forming a connection with G proteins, which turn on the phosphatidylinositol-calcium second messenger pathway, this alpha-adrenergic receptor exerts its effects. Proteins G(q) and G(11) mediate its effects. In cardiac myocytes, phenylephrine (PE)-stimulated ERK signaling is regulated by nuclear ADRA1A-ADRA1B heterooligomers.
Full Name | Adrenoceptor alpha 1B |
Gene ID | Human: 147 Mouse: 11548 Rat: 24173 Monkey: 695106 |
UniProt ID | Human: P35368 Mouse: P97717 Rat: P15823 Monkey: A0A2K5VRK3 |
Alternative Names | ADRA1; ALPHA1BAR; adrenergic, alpha-1B-, receptor; alpha-1B adrenoceptor; alpha-1B adrenoreceptor; ADRA1B; Adrenoceptor alpha 1B |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRA1B Target Family: Adrenoceptor Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRA1B Target Family: Adrenoceptor Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRA1B Target Family: Adrenoceptors Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Tools
- Target Protein: ADRA1B Target Family: Adrenergic Family
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRA1B Target Family: Adrenergic Family Target Protein Species: Human Host Cell Type: THP-1;CHO-K1;HEK293