ADRA1A
Prostatic hypertrophy and Horner's Syndrome are two conditions linked to ADRA1A. Activation of cAMP-Dependent PKA and Monoamine GPCRs are two of its associated pathways. G protein-coupled receptor activity and alpha1-adrenergic receptor activity are two GO annotations for this gene. By forming a connection with G proteins, which turn on the phosphatidylinositol-calcium second messenger pathway, this alpha-adrenergic receptor exerts its effects. Proteins G(q) and G(11) mediate its effects. In cardiac myocytes, phenylephrine(PE)-stimulated ERK signaling is regulated by nuclear ADRA1A-ADRA1B heterooligomers.
| Full Name | Adrenoceptor alpha 1A |
| Gene ID | Human: 148 Mouse: 11549 Rat: 29412 Monkey: 712509 |
| UniProt ID | Human: P35348 Mouse: P97718 Rat: P43140 Monkey: A0A2K6SDD6 |
| Alternative Names | ADRA1C; ADRA1L1; ALPHA1AAR; G protein coupled receptor; alpha-1A adrenoceptor; alpha-1A adrenoreceptor; alpha-1C adrenergic receptor; ADRA1A; Adrenoceptor alpha 1A |
Product List
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Magic™ Human ADRA1A Cell Line with 14-3-3ε Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX133]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRA1A Target Family: Adrenergic Family Target Protein Species: Human Protein Tag: TEV protease Assay Types: 14-3-3 assay
Magic™ Human ADRA1A CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay
[CAT#: S01YF-1222-KX380]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRA1A Target Family: Adrenoceptor Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human ADRA1A CHO-K1 Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay
[CAT#: S01YF-1222-KX13]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRA1A Target Family: Adrenoceptor Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Reporter Assay
Magic™ Human ADRA1A CHO-K1 Cell Line, Binding and Functional Assay
[CAT#: S01YF-1222-KX375]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRA1A Target Family: Adrenoceptor Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
Magic™ Human ADRA1A Lentivirus
[CAT#: S01YF-0922-KX1584]
- Product Category:
- Membrane Protein Tools
- Target Protein: ADRA1A Target Family: Adrenergic Family
Magic™ Human ADRA1A U2OS Cell Line with pLuc Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX102]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRA1A Target Family: Adrenergic Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
Magic™ Human FLAG tagged ADRA1A CHO-K1 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX189]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRA1A Target Family: Adrenergic Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ mPro Human ADRA1A Cell Line
[CAT#: S01YF-1122-KX8]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRA1A Target Family: Adrenoceptors Receptors Target Protein Species: Human
mProX™ Human ADRA1A Stable Cell Line
[CAT#: S01YF-0923-PY5]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ADRA1A Target Family: Adrenergic Family Target Protein Species: Human Host Cell Type: SMMC-7721;CHO-K1;HEK293
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