mProX™ Human TSSK1B Stable Cell Line

[CAT#: S01YF-1023-PY120]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1222-KX515	Magic™ Human TSSK1 in Vitro Assay	Human		Kinase Assay

Product Information

Target Family

Kinases/Enzyme

Target Protein Species

Human

Host Cell Type

HEK293;CHO-K1

Target Classification

Kinase Cell Lines

Target Research Area

Orphan Receptor Research

Related Diseases

Stiff Skin Syndrome; Ciliary Dyskinesia, Primary, 19

Gene ID

Human:83942

UniProt ID

Human:Q9BXA7

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

TSSK1B is a testis-specific serine kinase that has been studied in the context of sexual maturity, male infertility, and male contraception. In terms of sexual maturity, TSSK1B is one of the candidate genes that are under positive selection and play a role in testicular maturation. It is highly expressed in the testes and may be involved in enhancing boar reproductive traits. In the field of male infertility, mutations in TSSK1B have been associated with asthenoteratozoospermia, azoospermia, and teratozoospermia. These mutations may be a cause of undiagnosed cases of male infertility and should be considered in molecular diagnostics. Additionally, TSSK1B has been investigated as a potential target for male contraception, and computational methods have been used to study its binding affinity to inhibitors. Overall, TSSK1B is an important gene involved in testicular development, male fertility, and potential contraceptive strategies.

Protocols

Please visit our protocols page.

Customer Reviews

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FAQ

chat Casey Smith (Verified Customer)

What is the role of TSSK1B in male contraception? Jun 16 2023

chat Patrick Liam (Creative Biolabs Scientific Support)

TSSK1B is a validated target for male contraception, with studies establishing a quantitative structure-activity relationship for inhibitors. Jun 16 2023

chat Alex Williams (Verified Customer)

How does TSSK1B expression relate to male infertility? Oct 19 2020

chat Patrick Liam (Creative Biolabs Scientific Support)

TSSK1B is specifically expressed in testes and its expression patterns in yak and cattle-yak hybrids suggest a role in male fertility. Oct 19 2020

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