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    mProX™ Human TNFRSF14 Stable Cell Line

    [CAT#: S01YF-1023-PY240]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Oncology Cell Lines

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    Product Information

    Target Family
    Oncology
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1;T24;EJ
    Target Classification
    Oncology Cell Lines
    Target Research Area
    Infectious Research
    Related Diseases
    Herpes Simplex; Ezb Diffuse Large B-Cell Lymphoma
    Gene ID
    Human:8764
    UniProt ID
    Human:Q92956

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    TNFRSF14, also known as HVEM (herpesvirus entry mediator), plays a pivotal role in the modulation of immune responses. Recent studies have highlighted its significance in the context of immune checkpoint pathways. Specifically, TNFRSF14 has been identified as a potential therapeutic target for enhancing antitumor immunity. Its interaction with BTLA, a co-inhibitory receptor, has been shown to regulate T cell responses, making it a focal point in cancer immunotherapy research. Furthermore, the modulation of TNFRSF14 can influence the balance between stimulatory and inhibitory signals in the immune system, offering avenues for therapeutic interventions in various diseases.

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    FAQ

    chat Peyton Johnson (Verified Customer)

    What is the significance of TNFRSF14 in rheumatoid arthritis susceptibility? Sep 01 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    TNFRSF14 polymorphisms, in combination with other genetic factors, can determine susceptibility to rheumatoid arthritis, highlighting its role in the genetic background of the disease. Sep 01 2020

    chat Skyler Smith (Verified Customer)

    How does TNFRSF14 contribute to breast cancer prognosis? Sep 09 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    TNFRSF14, along with other pyroptosis-related risk genes, can be used to evaluate prognosis and immune infiltration in breast cancer, suggesting its role as a tumor suppressor gene. Sep 09 2020

    Related Products by Target
    • Magic™ Human TNFRSF14 HEK293T Cell Line (CAT#: S01YF-0123-KX330)
    • mProX™ Human TNFRSF14 Stable Cell Line (CAT#: S01YF-1023-PY240)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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