mProX™ Human STK25 Stable Cell Line

[CAT#: S01YF-1023-PY135]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1222-KX530	Magic™ Human YSK1(STK25) in Vitro Assay	Human		Kinase Assay

Product Information

Target Family

Kinases/Enzyme

Target Protein Species

Human

Host Cell Type

HEK293;CHO-K1;LoVo;RKO

Target Classification

Kinase Cell Lines

Target Research Area

Cardiovascular Research

Related Diseases

Cerebral Cavernous Malformations; Cerebral Cavernous Malformations 3

Gene ID

Human:10494

UniProt ID

Human:O00506

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

STK25, a serine/threonine protein kinase, has been implicated in various biological processes and diseases. In COVID-19 patients, increased levels of autoantibodies against STK25 have been observed, suggesting a potential role in the male reproductive system complications associated with the disease. In bighead carp, STK25 is part of the STK gene family and is involved in immune-related biological functions. In cancer, STK25 has been linked to glucose and fatty acid metabolism, autophagy, cell polarity, apoptosis, and migration, making it a potential therapeutic target. Additionally, high expression of STK25 has been associated with poor overall survival in patients with acute myeloid leukemia. In endothelial cells, loss of STK24/25, which interacts with CCM proteins, leads to the activation of MEKK3 signaling and the development of cerebral cavernous malformation. Overall, STK25 has diverse applications in different biological processes and diseases.

Protocols

Please visit our protocols page.

Customer Reviews

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FAQ

chat Taylor Williams (Verified Customer)

How does STK25 affect hepatocellular carcinoma? Feb 05 2023

chat Patrick Liam (Creative Biolabs Scientific Support)

STK25 enhances hepatocellular carcinoma progression through the STRN/AMPK/ACC1 pathway, influencing lipid metabolism and energy reserve. Feb 05 2023

chat Morgan Davis (Verified Customer)

What is the role of STK25 in allergic airway inflammation? Oct 20 2020

chat Patrick Liam (Creative Biolabs Scientific Support)

STK25 acts as a regulator of leukocyte migration and is involved in allergic airway inflammation. Oct 20 2020

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