mProX™ Human SRMS Stable Cell Line
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
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Published Data
Fig.1 Cisplatin treatment in vitro is rendered more sensitive through the process of SRMS silencing.
The cell viability of ovarian cancer ES-2 cells, with or without SRMS shRNA, was evaluated by treating cells with cisplatin (1.875 uM) or a vehicle control, and an assessment of cell viability was conducted through a viability assay after 72 h of treatment, in cells expressing two distinct SRMS shRNA clones or a control vector.
Ref: Jiang, Yunhan, et al. "ROS-mediated SRMS activation confers platinum resistance in ovarian cancer." Oncogene 42.20 (2023): 1672-1684.
Pubmed: 37020040
DOI: 10.1038/s41388-023-02679-6
Research Highlights
M Santana, Anthony. et al. "Chromatographic and spectroscopic analysis of Dibenzo[b,l]Fluoranthene and its determination in SRM 1597a by laser-excited time-resolved Shpol'skii spectroscopy." Analytica chimica acta, 2023.
Within the class of high molecular weight PAHs, there has been extensive research on the 302 Da molecules known as polycyclic aromatic hydrocarbons (PAHs). These specific PAHs are known to contribute significantly to the mutagenic and/or carcinogenic effects associated with PAHs found in both environmental and combustion-related samples. However, due to various factors such as the vast number of possible isomers, limited availability of reference standards, and low levels of concentration, the routine analysis of these 302 Da PAHs in environmental samples is not currently feasible.
M Santana, Anthony. et al. "Chromatographic and spectroscopic analysis of Dibenzo[b,l]Fluoranthene and its determination in SRM 1597a by laser-excited time-resolved Shpol'skii spectroscopy." Analytica chimica acta, 2023.
Pubmed:
37827650
DOI:
10.1016/j.aca.2023.341835
K Filipas, Dejan. et al. "The National Utilization of Non-Operative Management for Small Renal Masses Over 10 Years." JNCI cancer spectrum, 2023.
The management of small renal masses (SRMs) is commonly handled through non-operative methods. However, there is a lack of information regarding its utilization and the factors that may influence its usage. As such, a study was conducted to examine the patterns of non-operative management for SRMs and identify potential predictors. The findings of this study may contribute to a better understanding of the current practices in managing SRMs and aid in predicting the likelihood of non-operative approach in the future.
K Filipas, Dejan. et al. "The National Utilization of Non-Operative Management for Small Renal Masses Over 10 Years." JNCI cancer spectrum, 2023.
Pubmed:
37802923
DOI:
10.1093/jncics/pkad084
