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  • mProX™ Human SLAMF7 Stable Cell Line

    [CAT#: S01YF-1023-PY289]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:

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    Host Cell Type:
    Membrane Protein Engineering:
    Fluorescent Marker:
    Resistance:
    Deliverable:

    Product Information

    Target Family
    Other Targets
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1;RAW264.7
    Target Classification
    Other Targets Drug Discovery Assays and Products
    Target Research Area
    Cancer Research
    Related Diseases
    Plasmablastic Lymphoma; Smoldering Myeloma
    Gene ID
    Human:57823
    UniProt ID
    Human:Q9NQ25

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    SLAMF7, also known as CS1, is a protein that has been studied in various medical contexts. In IgG4-related disease (IgG4-RD), SLAMF7 is being evaluated as a potential target for treatment, along with other biologics and targeted agents. In plasmablastic lymphoma (PBL), SLAMF7 is being investigated as a diagnostic marker and a potential target for therapy. In silica particles-induced pulmonary inflammation, SLAMF7 is implicated in autophagy dysfunction and m6A modification. In multiple myeloma (MM), SLAMF7 is considered a promising immunotherapeutic target, and monoclonal antibodies targeting SLAMF7 have shown positive outcomes in clinical trials. Additionally, SLAMF7 has been identified as a biomarker associated with MM in liquid biopsy analysis. These studies highlight the diverse applications of SLAMF7 in different diseases and its potential as a therapeutic target.

    Protocols

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    FAQ

    chat Cameron Davis (Verified Customer)

    What is the significance of SLAMF7 in multiple myeloma? Jun 11 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    SLAMF7 is highly expressed on immunosuppressive T cells in multiple myeloma, suggesting that anti-SLAMF7 antibodies can boost anti-tumor immune responses in cancer patients. Jun 11 2021

    chat Alex Smith (Verified Customer)

    How does SLAMF7 expression influence macrophage activation in inflammation? Jan 31 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    SLAMF7 up-regulation on macrophages drives superactivation in inflammatory human diseases, indicating its role in both acute and chronic inflammatory conditions. Jan 31 2022
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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