mProX™ Human RPS6KA6 Stable Cell Line

[CAT#: S01YF-1023-PY94]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Bulk Quote

Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1222-KX483	Magic™ Human RSK4(RPS6KA6) in Vitro Assay	Human		Kinase Assay

Product Information

Target Family

Kinases/Enzyme

Target Protein Species

Human

Host Cell Type

HEK293;CHO-K1;DLD-1;HT29;SW480

Target Classification

Kinase Cell Lines

Target Research Area

Pain and Addiction Research

Related Diseases

Non-Syndromic X-Linked Intellectual Disability 77; Coffin-Lowry Syndrome

Gene ID

Human:27330

UniProt ID

Human:Q9UK32

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

RPS6KA6 (Ribosomal S6 kinase 4) has been implicated in various biological processes and diseases. In ovarian cancer, RPS6KA6 promoter methylation was observed, but it was not found to regulate its expression in ovarian cancer. In donkeys, RPS6KA6 was identified as a candidate gene associated with body size traits. In hepatocellular carcinoma, RPS6KA6 was part of an integrated RNA network and was found to be related to the prognosis of patients. In keratoconus, RPS6KA6 was identified as one of the candidate genes involved in the genetic spectrum of the disease. In different cancers, the expression of RPS6KA6 isoforms was found to be associated with clinical features, but the contradictory roles of RPS6KA6 in cancers cannot be explained solely by differential isoform expression. Further research is needed to understand the context-dependent function of RPS6KA6.

Protocols

Please visit our protocols page.

Customer Reviews

There are currently no Customer reviews or questions for mProX™ Human RPS6KA6 Stable Cell Line (S01YF-1023-PY94). Click the button above to contact us or submit your feedback about this product.

FAQ

chat Morgan Brown (Verified Customer)

How does RPS6KA6 affect thyroid cancer? Feb 08 2023

chat Patrick Liam (Creative Biolabs Scientific Support)

RPS6KA6 is regulated by FOXP2 and plays a role in thyroid cancer cell proliferation and apoptosis, possibly via the PI3K/AKT pathway. Feb 08 2023

chat Skyler Smith (Verified Customer)

What is the significance of RPS6KA6 in acute myeloid leukemia? Feb 27 2020

chat Patrick Liam (Creative Biolabs Scientific Support)

Down-regulation of RPS6KA6 in acute myeloid leukemia may lead to increased activity of the ERK/MPAK pathway, exacerbating leukemogenesis. Feb 27 2020

Related Products by Target

Online Inquiry

Thank you for your interest in mProX™ Human RPS6KA6 Stable Cell Line. Please provide us with your contact information and your local representative will contact you with a customized quote. Where appropriate, they can also assist you with a(n):

Estimated delivery time for your area;
Product sample or exclusive offer;
In-lab demonstration;

Creative Biolabs does not share your email address with third parties. Creative Biolabs will use your email address to confirm your identity and send you transaction-related emails, promotional and customer service emails in accordance with our privacy policy. You can change your email preferences at any time.