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  • mProX™ Human PRKX Stable Cell Line

    [CAT#: S01YF-1023-PY80]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Kinase Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
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    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-1222-KX461 Magic™ Human PRKX in Vitro Assay Human Kinase Assay

    Product Information

    Target Family
    Kinases/Enzyme
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1;HUVECs
    Target Classification
    Kinase Cell Lines
    Target Research Area
    Cancer Research
    Related Diseases
    Asbestos-Related Lung Carcinoma; Breast Ductal Adenoma
    Gene ID
    Human:5613
    UniProt ID
    Human:P51817

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    PRKX, or X-linked protein kinase, has various applications in different fields. In the field of food science, a study evaluated the effect of multi-frequency ultrasound treatment on the structural characteristics of beef myofibrillar proteins with different degrees of doneness. They found that PRKX, along with other factors, altered the structural characteristics of the proteins. In the field of developmental biology, PRKX was found to play a role in the miRNA profiling of developing rat retina, specifically during the first three postnatal weeks. In the field of emergency medicine, PRKX was identified as one of the predictors for neurological outcome after cardiac arrest. It was found to be down-regulated in peripheral blood mononuclear cells and showed potential in predicting the outcome. In the field of immunology, PRKX was found to down-regulate TAK1/IRF7 signaling in the antiviral innate immunity of black carp. Finally, in the field of oncology, PRKX was found to be upregulated in osteosarcoma and encouraged its progression. It was identified as a potential therapeutic target for the disease.

    Protocols

    Please visit our protocols page.

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    FAQ

    chat Taylor Williams (Verified Customer)

    How does PRKX influence ovarian cancer progression? Jan 24 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    PRKX is involved in ovarian cancer progression via the miR-744-5p/PRKX axis, impacting cell proliferation, migration, and invasion. Jan 24 2020

    chat Alex Smith (Verified Customer)

    What is the significance of PRKX in sex development disorders? Aug 30 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    PRKX/PRKY-mediated Xp;Yp translocations contribute significantly to SRY-positive 46,XX testicular disorders of sex development. Aug 30 2022
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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