mProX™ Human PRKG2 Stable Cell Line

[CAT#: S01YF-1123-KX192]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1122-KX1078	Magic™ Human CGK2(PRKG2) in Vitro Assay	Human		Kinase Assay

Product Information

Target Protein

PRKG2

Target Family

Kinases/Enzyme Drug Discovery Assays and Products

Target Protein Species

Human

Host Cell Type

CHO-K1; HEK293

Target Classification

Kinase Cell Lines

Related Diseases

Spondylometaphyseal Dysplasia, Pagnamenta Type and Acromesomelic Dysplasia 4. Among its related pathways are RAF/MAP kinase cascade and Metabolism of water-soluble vitamins and cofactors

Gene ID

5593

UniProt ID

Q13237

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The prkg2 gene encodes the cGMP-dependent protein kinase 2, a member of the serine/threonine kinase family. The regulation of endochondral ossification and the proliferation of gastrointestinal and nervous system cells are crucial functions of the prkg2 gene, which is extensively expressed in the brain, intestinal mucosa, and lungs. Prkg2 is extensively expressed in lung epithelial cells, particularly in alveolar type 2 (AT2) cells, according to earlier research. Differentiated AT2 cells have also shown a high expression level of prkg2 throughout lung development. Prkg2 has been demonstrated to stop lung cancer cells from growing, but it is unclear how prkg2 affects alveolar epithelial cells' homeostasis. The customized PRKG2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Sandra

High quality and reliable PRKG2 cell line. Apr 20 2021

chat Verified Customer

chat Dorothy

This PRKG2 cell line saved us time and resources. Plus, the technical support from the company was outstanding-prompt and helpful. May 26 2023

chat Verified Customer

FAQ

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