mProX™ Human PRKG1 Stable Cell Line

[CAT#: S01YF-1023-PY50]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1222-KX428	Magic™ Human PGK(PRKG1) in Vitro Assay	Human		Kinase Assay

Product Information

Target Family

Kinases/Enzyme

Target Protein Species

Human

Host Cell Type

HEK293;CHO-K1;Neonatal rat ventricle cardiomyocytes (CMs)

Target Classification

Kinase Cell Lines

Target Research Area

Cardiovascular Research

Related Diseases

Aortic Aneurysm, Familial Thoracic 8; Familial Thoracic Aortic Aneurysm And Aortic Dissection

Gene ID

Human:5592

UniProt ID

Human:Q13976

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

PRKG1 (protein kinase, cGMP-dependent, type I) is associated with various traits and conditions. In Zhaotong cattle, PRKG1 is identified as a candidate gene related to meat quality traits. In aging rats, impaired nitric oxide mechanisms, including PRKG1, are implicated in lower urinary tract dysfunction. In male NongHua ma ducks, PRKG1 is considered an important candidate marker gene related to neck ring formation. In individuals with rape pollen allergy, PRKG1 is identified as one of five characteristic genes associated with the condition. Additionally, in individuals with functional somatic syndromes, such as chronic fatigue syndrome and fibromyalgia syndrome, altered DNA methylation of PRKG1 is observed, potentially contributing to the pathophysiology of these conditions. Overall, PRKG1 has implications in bone development and metabolism, meat quality traits, immune response, heat resistance, lower urinary tract function, neck ring formation, pollen allergy, and functional somatic syndromes.

Protocols

Please visit our protocols page.

Customer Reviews

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FAQ

chat Peyton Johnson (Verified Customer)

How does PRKG1 influence achalasia disease? Jan 26 2021

chat Patrick Liam (Creative Biolabs Scientific Support)

Downexpression of miR-200c-3p contributes to achalasia disease by targeting the PRKG1 gene, suggesting its involvement in the disease's pathogenesis. Jan 26 2021

chat Morgan Johnson (Verified Customer)

What is the role of PRKG1 in skeletal muscle aging? Apr 03 2020

chat Patrick Liam (Creative Biolabs Scientific Support)

PRKG1-AS1, a long non-coding RNA, is identified as playing important roles in skeletal muscle aging, influencing cell viability and apoptosis. Apr 03 2020

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