mProX™ Human PPARD Stable Cell Line

[CAT#: S01YF-1123-KX104]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Nuclear Receptor

Certificate of Analysis Lookup
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Lot Number

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Product Information

Target Protein

PPARD

Target Family

Peroxisome Proliferator-activated Receptor

Target Protein Species

Human

Host Cell Type

HepG2; CHO-K1; HEK293

Target Classification

Nuclear Receptor

Target Research Area

Diabetes Research; Metabolic Research

Related Diseases

Diabetic Cataract; Abdominal Obesity-Metabolic Syndrome

Gene ID

5467

UniProt ID

Q03181

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

Nuclear receptors such as peroxisome proliferator-activated receptor delta (PPAR-delta) are encoded by the PPARD gene in humans. Numerous biological processes are regulated by PPAR-delta, which may also have a role in the emergence of multiple chronic illnesses, such as diabetes, obesity, atherosclerosis, and cancer. Exercise increases muscle PPARD expression, which raises oxidative capacity (the ability to burn fat) and increases type I fibers. Agonists for AMPK and PPAR-delta are considered to be exercise mimics. PPAR-β/δ raises oxidation and uncouples oxidative phosphorylation in adipose tissue. Studies using animals lacking this protein have indicated that it is involved in the myelination of the corpus callosum, the proliferation of epidermal cells, and the metabolism of fats and carbohydrates. The customized PPARD stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Jessica

I think this PPARD cell line is better than many similar products already on the market. Apr 08 2023

chat Verified Customer

chat Michael

This is a very reliable PPARD KO cell line with high sensitivity and specificity, suitable for experiments. Apr 17 2023

chat Verified Customer

FAQ

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