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  • mProX™ Human P2RX2 Stable Cell Line

    [CAT#: S01YF-1023-PY253]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:

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    Host Cell Type:
    Membrane Protein Engineering:
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    Product Information

    Target Family
    Other Targets
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1
    Target Classification
    Other Targets Drug Discovery Assays and Products
    Target Research Area
    CNS Research
    Related Diseases
    Deafness, Autosomal Dominant 41; Rare Autosomal Dominant Non-Syndromic Sensorineural Deafness Type Dfna
    Gene ID
    Human:22953
    UniProt ID
    Human:Q9UBL9

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The P2RX2 gene has various applications in different fields. In the context of genetic hearing loss, P2RX2 is involved in the diagnosis, management, and genetic counseling of this condition. In prostate cancer, P2RX2 is identified as a biomarker for prognosis and immune infiltration levels, and its downregulation is associated with poor survival. In cases of overactive bladder, P2RX2 is one of the genes implicated in the condition, and its expression is upregulated. Additionally, in a study on learning and memory impairment, disruption of P2RX2 signaling in the hippocampus was found to contribute to cognitive dysfunction. Overall, P2RX2 has implications in genetic hearing loss, prostate cancer, overactive bladder, and cognitive function.

    Protocols

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    Customer Reviews

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    FAQ

    chat Skyler Smith (Verified Customer)

    How does P2RX2 expression relate to prostate cancer prognosis? Nov 28 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    P2RX2 has been identified as a biomarker for early diagnosis, prognosis prediction, and aiding treatment decisions in prostate cancer, with its expression associated with clinical outcomes and immune infiltration. Nov 28 2020

    chat Jordan Miller (Verified Customer)

    What is the role of P2RX2 in hearing loss? Jul 30 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Mutations in the P2RX2 gene are associated with autosomal dominant deafness, with its role being essential for acoustic information transfer and hearing function. Jul 30 2020
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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