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    mProX™ Human NOD1 Stable Cell Line

    [CAT#: S01YF-1023-PY297]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:

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    Product Information

    Target Family
    Other Targets
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1;AGS
    Target Classification
    Other Targets Drug Discovery Assays and Products
    Target Research Area
    Digestive and Renal Research;Inflammation Research
    Related Diseases
    Crohn's Disease; Inflammatory Bowel Disease
    Gene ID
    Human:10392
    UniProt ID
    Human:Q9Y239

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    NOD1, a nucleotide-binding oligomerization domain-containing protein, has various applications in different fields. In septic cardiomyopathy, NOD1 is identified as one of the pyroptosis-related genes (PRGs) involved in the regulation of disease formation and progression. NOD1 is also involved in the recognition of bacterial cell wall components and activation of innate immune responses. Additionally, NOD1 has been studied in the context of extracellular vesicles released by probiotic bacteria, which have shown anti-allergic effects. In ovarian cancer, a pyroptosis-related long non-coding RNA signature involving NOD1 has been identified for prognosis and the construction of a ceRNA regulatory network. Furthermore, NOD1 has been recognized as a potential therapeutic target for the treatment of inflammatory diseases and cancer.

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    FAQ

    chat Jordan Jones (Verified Customer)

    How does NOD1 contribute to the immune response against bacterial infections? Sep 04 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    NOD1 plays a significant role in the immune response against bacterial infections by modulating epithelial and dendritic cell responses, leading to T cell polarization towards inflammatory responses. Sep 04 2023

    chat Jordan Brown (Verified Customer)

    What is the significance of NOD1 in inflammatory diseases? Jan 09 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    NOD1 is linked to various inflammatory diseases, including Crohn's disease, asthma, diabetes, and obesity, due to its role in regulating inflammatory responses. Jan 09 2020

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    • Magic™ Human NOD1 HEK293 Cell Line with SEAP Reporter (CAT#: S01YF-0123-KX380)
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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