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    mProX™ Human MUSK Stable Cell Line

    [CAT#: S01YF-1023-PY20]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Kinase Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
    Fluorescent Marker:
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    Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

    Sub Cat Product Name Target Protein Species Host Cell Type Assay Types Inquiry Datasheet
    S01YF-1222-KX395 Magic™ Human MUSK in Vitro Assay Human Kinase Assay

    Product Information

    Target Family
    Kinases/Enzyme
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1;HCCLM3
    Target Classification
    Kinase Cell Lines
    Target Research Area
    CNS Research
    Related Diseases
    Fetal Akinesia Deformation Sequence 1; Myasthenic Syndrome, Congenital, 9, Associated With Acetylcholine Receptor Deficiency
    Gene ID
    Human:4593
    UniProt ID
    Human:O15146

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Musk (MUSK) has applications in various fields. In the field of healthcare, it is used in the cost-effectiveness evaluation of stroke prevention strategies for atrial fibrillation. Studies have shown that left atrial appendage closure (LAAC) is a cost-effective option compared to other treatments. Musk is also used in the analysis of volatile compounds in plants, specifically in carrot varieties that affect honey bee feeding. Additionally, musk is involved in the study of Myasthenia Gravis (MG), an autoimmune disease, and the development of therapeutic strategies. Rituximab, a drug used in MG treatment, has shown effectiveness in MuSK-positive patients, but results are variable for AChR-positive patients. Further research is needed to optimize treatment protocols and monitor the safety and efficacy of musk-based therapies. Musk is also used in environmental studies to analyze organic pollutants released from atmospheric particles, helping to estimate their inhalation bioaccessibility and bioavailability.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human MUSK Stable Cell Line (S01YF-1023-PY20). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Jordan Johnson (Verified Customer)

    What is the role of MuSK in neuromuscular junction formation? Nov 24 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    MuSK, a receptor tyrosine kinase, is essential for neuromuscular junction (NMJ) formation and is activated by a complex involving Lrp4 and Agrin​​​​. Nov 24 2022

    chat Skyler Jones (Verified Customer)

    How are MuSK antibodies related to myasthenia gravis? May 06 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Autoantibodies to MuSK are found to cause myasthenia gravis (MG), and the immunization with MuSK or transfer of IgG fractions from patients reproduced myasthenic muscle weakness in animal models​​. May 06 2023

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    • mProX™ Human MUSK Stable Cell Line (CAT#: S01YF-1023-PY20)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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