mProX™ Human MUSK Stable Cell Line

R Quarrell, Stephen. et al. "Critical Pollination Chemistry: Specific Sesquiterpene Floral Volatiles in Carrot Inhibit Honey Bee Feeding." Journal of agricultural and food chemistry, 2023.
In the context of insect pollination in plants, many agricultural breeding programs prioritize traits attractive to growers and consumers rather than pollinators, causing reduced pollinator attraction and crop yields. A study using hybrid carrot seed production as a case study examined low-yielding carrot varieties, focusing on nectar composition and floral volatiles. While nectar analysis showed no significant differences, analysis of the 112 detected volatiles in 23 samples revealed variations. Specific sesquiterpenes, such as β-ocimene (an attractant) from high-yielding carrot varieties and α- and β-selinene (deterrents) from low-yielding lines, affected nectar feeding behavior. These findings underscore the role of volatiles in regulating pollinator attraction in agricultural contexts, suggesting a trade-off between pollination and plant protection.
R Quarrell, Stephen. et al. "Critical Pollination Chemistry: Specific Sesquiterpene Floral Volatiles in Carrot Inhibit Honey Bee Feeding." Journal of agricultural and food chemistry, 2023.
Pubmed: 37871312   DOI: 10.1021/acs.jafc.3c03392

Chen, Xin. et al. "Myasthenia gravis: Molecular mechanisms and promising therapeutic strategies." Biochemical pharmacology, 2023.
Myasthenia gravis (MG) is an autoimmune disease that results in the blockage of neuromuscular junction transmission due to autoantibodies attacking transmission-related proteins. The most commonly detected antibodies in MG patients are anti-AChR, anti-MuSK, and anti-LRP4. While traditional therapies can manage most symptoms of MG, there are still challenges to overcome, prompting the need for more effective and safer treatment options. Recent research on the mechanism and immune targets of MG has led to the development of biological therapies. However, these novel treatments may compromise the patient's immunity and increase the risk of infection. This article discusses the pathogenesis of MG and compares the benefits and drawbacks of traditional and biological treatment strategies. It also highlights the potential of combined therapy to improve effectiveness and reduce side effects in MG treatment. As research on immunotherapy targets in MG continues to advance, new opportunities and challenges for treating this condition will emerge.
Chen, Xin. et al. "Myasthenia gravis: Molecular mechanisms and promising therapeutic strategies." Biochemical pharmacology, 2023.
Pubmed: 37865142   DOI: 10.1016/j.bcp.2023.115872