mProX™ Human MARK3 Stable Cell Line
[CAT#: S01YF-1123-KX301]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
MARK3
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Ocular Research; Pigmentation Research; Reproductive Research
Related Diseases
Visual Impairment And Progressive Phthisis Bulbi and Peutz-Jeghers Syndrome. Among its related pathways are Signaling downstream of RAS mutants and RAF/MAP kinase cascade
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
A member of the MARK family, microtubule affinity-regulating kinase 3 (MARK3) controls the differentiation of ciliated cells, osteoclasts, and the cell cycle, among other critical pathways. Given that MARK3 has three domains-a ubiquitin-associated domain, a C-terminal kinase-associated domain, and an N-terminal serine/threonine kinase domain-all of which carry out various regulatory tasks, it is critical to comprehend how their actions are regulated. These include interactions with other proteins and scaffolding, as well as post-translational modifications like phosphorylation. According to recent research, MARK3 may be involved in a number of clinical disorders, such as cancer, osteoporosis, and congenital blepharophimosis syndrome. The customized MARK3 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Karen
With the mouse MARK3 KO cell line, I can now complete my experiments in a fraction of the time.
Aug 05 2023
Verified Customer
Rebecca
The MARK3 cell line is a cost-effective solution.
Oct 07 2021
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
